Article
Genome-wide association study of IgG1 responses to the choline-binding protein PspC of Streptococcus pneumoniae.
Genes and immunity - 1 Jan 2000
Anderson D, Fakiola M, Hales B J, Pennell C E, Thomas W R, Blackwell J M
Abstract excerpt
Streptococcus pneumoniae causes invasive pneumococcal disease. Delayed development of antibodies to S. pneumoniae in infancy is associated with the development of atopy and asthma. Pneumococcal surface protein C (PspC) is a vaccine candidate and variation in its choline-binding region is associated with invasive disease. This study examined 523 060 single-nucleotide polymorphisms in The Western Australian...
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