Article
The link between genetic variation and variability in vaccine responses: systematic review and meta-analyses.
Vaccine - 26 Mar 2014
Posteraro Brunella, Pastorino Roberta, Di Giannantonio Paolo, Ianuale Carolina, Amore Rosarita, Ricciardi Walter, Boccia Stefania
Abstract excerpt
Although immune response to vaccines can be influenced by several parameters, human genetic variations are thought to strongly influence the variability in vaccine responsiveness. Systematic reviews and meta-analyses are needed to clarify the genetic contribution to this variability, which may affect the efficacy of existing vaccines. We performed a systematic literature search to identify all studies describing...
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