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Article

Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.

Vaccine - 25 Mar 2008

Dhiman Neelam, Ovsyannikova Inna G, Vierkant Robert A, Ryan Jenna E, Pankratz V Shane, Jacobson Robert M, Poland Gregory A

Abstract excerpt

Toll-like receptors (TLRs) represent the critical "bridge" between innate and adaptive immunity to viral pathogens. We hypothesized that single nucleotide polymorphisms (SNPs) that potentially influence the expression/function of TLRs and their associated intracellular signaling molecules contribute to variations in humoral and cellular immunity to measles vaccine. We genotyped 190 randomly selected subjects...

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Source

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Identifiers

PMID: 18325643
DOI: 10.1016/j.vaccine.2008.01.017
PMCID: PMC2292110

Genes

TLR3
TLR4
TLR5
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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