Article
Role of Maternal Antibodies in Infants with Severe Diseases Related to Human Parechovirus Type 3.
Emerging infectious diseases - 1 Nov 2015
Aizawa Yuta, Watanabe Kanako, Oishi Tomohiro, Hirano Harunobu, Hasegawa Isao, Saitoh Akihiko
Abstract excerpt
Human parechovirus type 3 (HPeV3) is an emerging pathogen that causes sepsis and meningoencephalitis in young infants. To test the hypothesis that maternal antibodies can protect this population, we measured neutralizing antibody titers (NATs) to HPeV3 and other genotypes (HPeV1 and HPeV6) in 175 cord blood samples in Japan. The seropositivity rate (≥1:32) for HPeV3 was 61%, similar to that for the other...
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