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Article

Circular RNAs are depleted of polymorphisms at microRNA binding sites.

Bioinformatics (Oxford, England) - 15 Aug 2014

Thomas Laurent F, Sætrom Pål

Abstract excerpt

MOTIVATION: Circular RNAs (circRNAs) are an abundant class of highly stable RNAs that can affect gene regulation by binding and preventing microRNAs (miRNAs) from regulating their messenger RNA (mRNA) targets. Mammals have thousands of circRNAs with predicted miRNA binding sites, but only two circRNAs have been verified as being actual miRNA sponges. As it is unclear whether these thousands of predicted miRNA...

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Identifiers

PMID: 24764460
DOI: 10.1093/bioinformatics/btu257
PMCID: PMC4207428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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