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Article

Effects of genetic variations on microRNA: target interactions.

Nucleic acids research - 1 Sept 2014

Liu Chaochun, Rennie William A, Carmack C Steven, Kanoria Shaveta, Cheng Jijun, Lu Jun, Ding Ye

Abstract excerpt

Genetic variations within microRNA (miRNA) binding sites can affect miRNA-mediated gene regulation, which may lead to phenotypes and diseases. We perform a transcriptome-scale analysis of genetic variants and miRNA:target interactions identified by CLASH. This analysis reveals that rare variants tend to reside in CDSs, whereas common variants tend to reside in the 3' UTRs. miRNA binding sites are more likely to...

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Identifiers

PMID: 25081214
DOI: 10.1093/nar/gku675
PMCID: PMC4150780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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