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Article

Transcription of methylated viral DNA by eukaryotic RNA polymerase II.

Cell biophysics - 1 Jan 2000

Willis D B, Thompson J P, Essani K, Goorha R

Abstract excerpt

The genome of the large icosahedral DNA virus, frog virus 3 (FV3), is heavily methylated at the cytosine residues of dCdG dinucleotide pairs, with more than 22% of the total cytosine residues in the form of 5-methylcytosine (5mC). This methylation is carried out postreplicatively in the cytoplasm of infected cells by a virus-encoded DNA methyltransferase. DNA methyltransferase activity was shown to copurify with...

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PMID: 2476231
DOI: 10.1007/BF02991583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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