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Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity

1 Jun 2012

Abstract excerpt

Human Cytomegalovirus (HCMV) is a ubiquitous herpesvirus that infects and establishes latency in the majority of the human population and may cause fatal infections in immunocompromised patients. Recent data implies a close interaction between HCMV encoded proteins and cellular epigenetic mechanisms such as histone acetylation and deacetylation. In this study, we investigated the interactions between HCMV...

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PMID: 22595877
DOI: 10.4161/epi.20075

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