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Article

Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation.

Journal of virology - 1 Oct 2001

Fang J Y, Mikovits J A, Bagni R, Petrow-Sadowski C L, Ruscetti F W

Abstract excerpt

DNA methylation, by regulating the transcription of genes, is a major modifier of the eukaryotic genome. DNA methyltransferases (DNMTs) are responsible for both maintenance and de novo methylation. We have reported that human immunodeficiency virus type 1 (HIV-1) infection increases DNMT1 expression and de novo methylation of genes such as the gamma interferon gene in CD4(+) cells. Here, we examined the...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Genes, p16

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Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 11559808
DOI: 10.1128/JVI.75.20.9753-9761.2001
PMCID: PMC114547

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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