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Article

DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV‐1 infection

11 Mar 2015

Abstract excerpt

Viral infections can alter the cellular epigenetic landscape, through modulation of either DNA methylation profiles or chromatin remodeling enzymes and histone modifications. These changes can act to promote viral replication or host defense. Herpes simplex virus type 1 (HSV-1) is a prominent human pathogen, which relies on interactions with host factors for efficient replication and spread. Nevertheless, the...

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PMID: 25758154
DOI: 10.1002/pmic.201500035

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