Article
Viral genome methylation as an epigenetic defense against geminiviruses.
Journal of virology - 1 Sept 2008
Raja Priya, Sanville Bradley C, Buchmann R Cody, Bisaro David M
Abstract excerpt
Geminiviruses encapsidate single-stranded DNA genomes that replicate in plant cell nuclei through double-stranded DNA intermediates that associate with cellular histone proteins to form minichromosomes. Like most plant viruses, geminiviruses are targeted by RNA silencing and encode suppressor proteins such as AL2 and L2 to counter this defense. These related proteins can suppress silencing by multiple mechanisms,...
Topics
- Adenosine Kinase
- Arabidopsis
- Chromatin
- DNA, Viral
- DNA-Cytosine Methylases
- Epigenesis, Genetic
- Geminiviridae
- Genome, Viral
- Histone-Lysine N-Methyltransferase
- Histones
- Methylation
