Article
SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.
Cancer investigation - 1 Jul 2014
Bui Hoai Thi Thu, Fujimoto Naohiro, Kubo Tatsuhiko, Inatomi Hisato, Matsumoto Tetsuro
Abstract excerpt
A variety of carcinogens are excreted in urine and may be actively transported by organic anion-transporting polypeptides that encoded by SLCOs. In this study, we evaluated whether single nucleotide polymorphisms (SNPs) in SLCO1B1, SLCO2B1, and SLCO1B3 are associated with bladder cancer susceptibility. Our results, for the first time, indicated that polymorphisms of SLCO1B1 rs2306283 might be associated with...
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