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Article

Establishment of gene copy number-specific normal ranges for serum C4 and its utility for interpretation in patients with chronically low serum C4 concentrations.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Sept 2014

Margery-Muir Audrey A, Wetherall John D, Castley Alison S L, Hew Meilyn, Whidborne Rebecca S, Mallon Dominic F J, Martinez Patricia, Witt Campbell S

Abstract excerpt

OBJECTIVE: To establish gene copy number (GCN)-specific normal ranges for serum C4 genes and to determine their utility with respect to the interpretation of chronically low serum C4 concentrations in patients with clinically quiescent systemic lupus erythematosus (SLE). METHODS: C4 serum concentrations were estimated by automated turbidimetry, and C4 GCNs were determined using the TaqMan real-time polymerase...

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PMID: 24757030
DOI: 10.1002/art.38680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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