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Article

Complement C4 Gene Copy Number Variation Genotyping by High Resolution Melting PCR.

International journal of molecular sciences - 31 Aug 2020

Jaimes-Bernal Claudia P, Trujillo Monte, Márquez Francisco José, Caruz Antonio

Abstract excerpt

BACKGROUND: Complement C4 gene copy number variation plays an important role as a determinant of genetic susceptibility to common diseases, such as systemic lupus erythematosus, schizophrenia, rheumatoid arthritis, and infectious diseases. This study aimed to develop an assay for the quantification of copy number variations in the C4 locus. METHODS: the assay was based on a gene ratio analysis copy enumeration...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32878183
DOI: 10.3390/ijms21176309
PMCID: PMC7504122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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