Article
Confirmation of C4 gene copy number variation and the association with systemic lupus erythematosus in Chinese Han population.
Rheumatology international - 1 Oct 2012
Lv Yongmei, He Sumin, Zhang Zheng, Li Yang, Hu Dayan, Zhu Kunju, Cheng Hui, Zhou Fusheng, Chen Gang, Zheng Xiaodong, Li Pan, Ren Yunqing, Yin Xianyong, Cui Yong, Sun Liangdan, Yang Sen, Zhang Xuejun
Abstract excerpt
The distribution of complement component 4 (C4) gene copy number (GCN) has been validated in European populations. Meanwhile, C4 gene has been identified as a susceptibility gene for systemic lupus erythematosus (SLE). However, the association and the possible phenotype significance remain to be determined intensely in the Chinese population. This study was designed to validate the distribution of C4 GCNs in...
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