Article
Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epithelium.
PloS one - 1 Jan 2014
Makarev Evgeny, Gorivodsky Marat
Abstract excerpt
Islet1 belongs to Lim homeobox (Lhx) gene family which encodes transcription factors that have been conserved in evolution. They form complexes with other transcriptional regulators, among them obligatory co-factors encoded by Ldb genes. Isl1 (Islet1), Lhx and Ldb1 genes play a crucial role in organ patterning, cell fate determination and cell differentiation in both embryonic and adult tissues. In this study we...
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