Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome.

The EMBO journal - 20 Sept 2006

Doyen Cécile-Marie, Montel Fabien, Gautier Thierry, Menoni Hervé, Claudet Cyril, Delacour-Larose Marlène, Angelov Dimitri, Hamiche Ali, Bednar Jan, Faivre-Moskalenko Cendrine, Bouvet Philippe, Dimitrov Stefan

Abstract excerpt

The histone variant H2A.Bbd appeared to be associated with active chromatin, but how it functions is unknown. We have dissected the properties of nucleosome containing H2A.Bbd. Atomic force microscopy (AFM) and electron cryo-microscopy (cryo-EM) showed that the H2A.Bbd histone octamer organizes only approximately 130 bp of DNA, suggesting that 10 bp of each end of nucleosomal DNA are released from the octamer. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Assembly and Disassembly
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cryoelectron Microscopy

Share to Microscopy, Atomic Force

Share to Nucleosomes

Share to Protein Structure, Quaternary

Share to Xenopus laevis

Share to Xenopus Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 16957777
DOI: 10.1038/sj.emboj.7601310
PMCID: PMC1570437

Genes

AFM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome.PMID 16957777Read ↗

Quickly evolving histones, nucleosome stability and chromatin folding: all about histone H2A.Bbd.Semantic proximity Read ↗

Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells.Semantic proximity Read ↗

The many tales of a tail: carboxyl-terminal tail heterogeneity specializes histone H2A variants for defined chromatin function.Semantic proximity Read ↗

H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesisSemantic proximity Read ↗

The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct from conventional H2B with respect to the assembly of mitotic chromosomes.Semantic proximity Read ↗

The histone variant H2A.Bbd is enriched at sites of DNA synthesis.Semantic proximity Read ↗

Molecular mechanism of histone variant H2A.B on stability and assembly of nucleosome and chromatin structures.Semantic proximity Read ↗

The dynamics of individual nucleosomes controls the chromatin condensation pathway: direct atomic force microscopy visualization of variant chromatin.Semantic proximity Read ↗

Assembly and disassembly of nucleosome core particles containing histone variants by human nucleosome assembly protein I.Semantic proximity Read ↗

Proteome analysis of protein partners to nucleosomes containing canonical H2A or the variant histones H2A.Z or H2A.X.Semantic proximity Read ↗

Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b.Semantic proximity Read ↗

Crystal structure of the overlapping dinucleosome composed of hexasome and octasome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.