Article
Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection.
Genes and immunity - 1 Aug 2000
Yee L J, Tang J, Herrera J, Kaslow R A, van Leeuwen D J
Abstract excerpt
Pro-inflammatory cytokines including tumour necrosis factor (TNF) mediate the pathogenesis of hepatitis C virus (HCV) infection. The distribution of TNF gene polymorphisms was examined among cirrhotic and non-cirrhotic patients infected with HCV. Thirty Caucasians with cirrhosis due to chronic HCV infection and 114 HCV-infected patients histopathologically free of cirrhosis were genotyped for genetic variants in...
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