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Article

Role of genetic polymorphisms of the dopaminergic system in Parkinson's disease patients with impulse control disorders.

Parkinsonism & related disorders - 1 May 2012

Vallelunga Annamaria, Flaibani Raffaella, Formento-Dojot Patrizia, Biundo Roberta, Facchini Silvia, Antonini Angelo

Abstract excerpt

BACKGROUND: The mechanisms underlying the development of impulse control disorders (ICDs) like compulsive gambling, buying, sexual, and eating behaviors in Parkinson's disease (PD) are debated. We assessed whether allelic variants of dopamine D2 receptors (DRD2), catechol-O-methyltransferase (COMT) and dopamine transporter (DAT) were associated with the development of ICDs in PD. METHOD: We enrolled 89 idiopathic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22113132
DOI: 10.1016/j.parkreldis.2011.10.019

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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