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Article

Mouse SCNT ESCs have lower somatic mutation load than syngeneic iPSCs.

Stem cell reports - 8 Apr 2014

Li Zhe, Lu Hongxia, Yang Weifeng, Yong Jun, Zhang Zhen-Ning, Zhang Kun, Deng Hongkui, Xu Yang

Abstract excerpt

Ectopic expression of reprogramming factors has been widely adopted to reprogram somatic nucleus into a pluripotent state (induced pluripotent stem cells [iPSCs]). However, genetic aberrations such as somatic gene mutation in the resulting iPSCs have raised concerns regarding their clinical utili...

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Identifiers

PMID: 24749065
DOI: 10.1016/j.stemcr.2014.02.005
PMCID: PMC3986627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24749065-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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