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Recent advances in the molecular genetics of type 2 diabetes mellitus

1 Jan 2014

Abstract excerpt

Type 2 diabetes mellitus (T2DM) is a complex disease in which both genetic and environmental factors interact in determining impaired β-cell insulin secretion and peripheral insulin resistance. Insulin resistance in muscle, liver and fat is a prominent feature of most patients with T2DM and obesity, resulting in a reduced response of these tissues to insulin. Considerable evidence has been accumulated to indicate...

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PMID: 24748926
DOI: 10.4239/wjd.v5.i2.128

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