Article
Genetics of type 2 diabetes mellitus.
Diabetes research and clinical practice - 1 Jun 2005
Malecki Maciej T
Abstract excerpt
The clinical picture of type 2 diabetes mellitus (T2DM) is formed by impairment in insulin secretion and resistance to insulin action. As a result of intensive efforts of the scientists around the world mutations and polymorphisms in a number of genes were linked with monogenic and polygenic forms of T2DM. Two major strategies were used in this research: genome scanning and the candidate gene approach. Monogenic...
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