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Article

Epigenetic Modifications Associated with the Pathogenesis of Type 2 Diabetes Mellitus

4 Mar 2019

Abstract excerpt

BACKGROUND AND OBJECTIVE: Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disorder. Pancreatic β-cell dysfunction and insulin resistance are the most common and crucial events of T2DM. Increasing evidence suggests the association of epigenetic modifications with the pathogenesis of T2DM through the changes in important biological processes including pancreatic β- cell differentiation, development...

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Diabetes and associated disorders
Epigenetics and DNA Methylation
Pancreatic function and diabetes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30827271
DOI: 10.2174/1871530319666190301145545

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