Article
HLA-G and inflammatory diseases.
Inflammation & allergy drug targets - 1 Jun 2008
Baricordi Olavio R, Stignani Marina, Melchiorri Loredana, Rizzo Roberta
Abstract excerpt
HLA-G antigens are non classical HLA-class I molecules characterized by a low allelic polymorphism, a limited tissue distribution and the presence of membrane bound and soluble isoforms. The HLA-G antigens were firstly detected in cytotrophoblast cells at the feto-maternal interface where they maintain a tolerogenic status between the mother and the semiallogenic fetus. Recently a variable expression of HLA-G...
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