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Article

Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina.

Current biology : CB - 29 Mar 2005

Mu Xiuqian, Fu Xueyao, Sun Hongxia, Liang Shuguang, Maeda Hidetaka, Frishman Laura J, Klein William H

Abstract excerpt

The vertebrate retina develops from an amorphous sheet of dividing retinal progenitor cells (RPCs) through a sequential process that culminates in an exquisitely patterned neural tissue. A current model for retinal development posits that sequential cell-type differentiation is the result of changes in the intrinsic competence state of multipotent RPCs as they advance in time and that the intrinsic changes are...

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Identifiers

PMID: 15797020
DOI: 10.1016/j.cub.2005.01.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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