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Article

Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse.

Development (Cambridge, England) - 1 Jan 2008

Mao Chai-An, Kiyama Takae, Pan Ping, Furuta Yasuhide, Hadjantonakis Anna-Katerina, Klein William H

Abstract excerpt

The mechanisms regulating retinal ganglion cell (RGC) development are crucial for retinogenesis and for the establishment of normal vision. However, these mechanisms are only vaguely understood. RGCs are the first neuronal lineage to segregate from pluripotent progenitors in the developing retina. As output neurons, RGCs display developmental features very distinct from those of the other retinal cell types. To...

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Identifiers

PMID: 18077589
DOI: 10.1242/dev.009688
PMCID: PMC2893890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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