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Article

Messenger RNA- versus retrovirus-based induced pluripotent stem cell reprogramming strategies: analysis of genomic integrity.

Stem cells translational medicine - 1 Jun 2014

Steichen Clara, Luce Eléanor, Maluenda Jérôme, Tosca Lucie, Moreno-Gimeno Inmaculada, Desterke Christophe, Dianat Noushin, Goulinet-Mainot Sylvie, Awan-Toor Sarah, Burks Deborah, Marie Joëlle, Weber Anne, Tachdjian Gérard, Melki Judith, Dubart-Kupperschmitt Anne

Abstract excerpt

The use of synthetic messenger RNAs to generate human induced pluripotent stem cells (iPSCs) is particularly appealing for potential regenerative medicine applications, because it overcomes the common drawbacks of DNA-based or virus-based reprogramming strategies, including transgene integration...

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Identifiers

PMID: 24736403
DOI: 10.5966/sctm.2013-0158
PMCID: PMC4039453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24736403-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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