Article
Characterization of breast cancers with PI3K mutations in an academic practice setting using SNaPshot profiling.
Breast cancer research and treatment - 1 Jun 2014
Abramson Vandana G, Cooper Lloyd M, Ballinger Tarah, Sanders Melinda E, Du Liping, Lai Darson, Su Zengliu, Mayer Ingrid, Levy Mia, LaFrance Delecia R, Vnencak-Jones Cindy L, Shyr Yu, Dahlman Kimberly B, Pao William, Arteaga Carlos L
Abstract excerpt
Mutations in the PIK3CA gene are common in breast cancer and represent a clinically useful therapeutic target. Several larger, population-based studies have shown a positive prognostic significance associated with these mutations. This study aims to further identify characteristics of patients harboring PIK3CA mutations while evaluating the clinical impact of genomic testing for these mutations. Tumors from 312...
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