Article
Association of the HLA-B*52 allele with non-progression to AIDS in Brazilian HIV-1-infected individuals.
Genes and immunity - 1 Apr 2014
Teixeira S L M, de Sá N B R, Campos D P, Coelho A B, Guimarães M L, Leite T C N F, Veloso V G, Morgado M G
Abstract excerpt
Several human leukocyte antigen (HLA) class I alleles are associated with the susceptibility to human immunodeficiency virus-1 (HIV-1) infection and/or AIDS progression. Of these, the HLA-B alleles are considered the strongest genetic determinant of disease outcome. We evaluated the influence of the HLA-B alleles on AIDS progression among HIV-1-positive individuals from Rio de Janeiro, Brazil, who were...
Topics
- Acquired Immunodeficiency Syndrome
- Adolescent
- Adult
- Alleles
- Brazil
- Female
- Gene Frequency
- HIV-1
- HLA-B52 Antigen
- Humans
- Male
- Middle Aged