Article
Progression of HIV to AIDS: a protective role for HLA-B27?
AIDS reviews - 1 Jan 2000
den Uyl Debby, van der Horst-Bruinsma Irene E, van Agtmael Michiel
Abstract excerpt
HLA-B27 is known for its strong association with inflammatory spondyloarthropathies (SpA), a group of rheumatic diseases. Apart from playing its role in the onset of these inflammatory diseases, HLA-827 is so ubiquitous in the world that the carrying of this gene must have also have an advantage. There are some indications that a beneficial effect can be found as a less severe course of viral infections among...
Topics
- Acquired Immunodeficiency Syndrome
- Alleles
- Disease Progression
- Genetic Predisposition to Disease
- HIV Infections
- HIV Long-Term Survivors
- HIV-1
- HLA-B27 Antigen
- Humans
- T-Lymphocytes, Cytotoxic