Article
Associations of HLA class I antigen specificities and haplotypes with disease progression in HIV-1-infected Hans in Northern China.
Human immunology - 1 Dec 2013
Zhang Hui, Zhao Bin, Han Xiaoxu, Wang Zhe, Liu Baogui, Lu Chunming, Zhang Min, Liu Jing, Chen Ou, Hu Qinghai, Jiang Fanming, Shang Hong
Abstract excerpt
The human leukocyte antigen (HLA) allele frequencies, which differ among various ethnic populations, may result in population-specific effects on HIV-1 disease progression. No large-scale study has yet been conducted on the Chinese population. In this study, HLA class I antigen specificities were determined in a cohort including 105 long-term non-progressors (LTNPs) and 321 typical progressors (TPs), who were...
Topics
- Adult
- Alleles
- Asian People
- China
- Disease Progression
- Female
- Gene Frequency
- HIV Infections
- HIV-1
- Haplotypes
- Histocompatibility Antigens Class I