Analysis of two autoimmunity genes, IRAK1 and MECP2, in giant cell arteritis.

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Article

Analysis of two autoimmunity genes, IRAK1 and MECP2, in giant cell arteritis.

Clinical and experimental rheumatology - 1 Jan 2000

Márquez Ana, Solans Roser, Hernández-Rodríguez José, Cid María C, Castañeda Santos, Ramentol Marc, Morado Inmaculada C, Rodriguez-Rodriguez Luis, Narváez Javier, Gómez-Vaquero Carmen, Miranda-Filloy José A, Martínez-Taboada Víctor M, Ríos Raquel, Sopeña Bernardo, Monfort Jordi, García-Villanueva María Jesús, Martínez-Zapico Aleida, Marí-Alfonso Begoña, Sánchez-Martín Julio, Unzurrunzaga Ainhoa, Raya Enrique, de Miguel Eugenio, Hidalgo-Conde Ana, Blanco Ricardo, González-Gay Miguel Ángel, Martín Javier

Abstract excerpt

OBJECTIVES: The Xq28 region, containing IRAK and MECP2, represent a common susceptibility locus for a high number of autoimmune diseases. Our aim in the present study was to evaluate the influence of the IRAK1 and MECP2 autoimmunity-associated genetic variants in the giant cell arteritis (GCA) susceptibility and its clinical subphenotypes. METHODS: We analysed a total of 627 female biopsy-proven GCA patients and...

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Identifiers

PMID: 24709033

Genes

MECP2
GCA
IRAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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