Article
Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica.
Seminars in arthritis and rheumatism - 1 Aug 2003
González-Gay Miguel A, Amoli Mahsa M, Garcia-Porrua Carlos, Ollier William E r
Abstract excerpt
BACKGROUND AND OBJECTIVES: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are common and often overlapping diseases that generally occur in elderly patients. In this article, we examine the role of different genes as markers of disease susceptibility and severity in GCA and PMR. METHODS: The influence of human leukocyte antigen (HLA)-DRB1 and tumor necrosis factor alleles, as well as the different...
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