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Article

Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.

Annals of the rheumatic diseases - 1 Nov 2013

Serrano A, Márquez A, Mackie S L, Carmona F D, Solans R, Miranda-Filloy J A, Hernández-Rodríguez J, Cid M C, Castañeda S, Morado I C, Narváez J, Blanco R, Sopeña B, García-Villanueva M J, Monfort J, Ortego-Centeno N, Unzurrunzaga A, Marí-Alfonso B, Sánchez Martín J, de Miguel E, Magro C, Raya E, Braun N, Latus J, Molberg O, Lie B A, Moosig F, Witte T, Morgan A W, González-Gay M A, Martín J

Abstract excerpt

OBJECTIVE: To analyse the role of the PTPN22 and CSK genes, previously associated with autoimmunity, in the predisposition and clinical phenotypes of giant cell arteritis (GCA). METHODS: Our study population was composed of 911 patients diagnosed with biopsy-proven GCA and 8136 unaffected control...

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Source

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Identifiers

PMID: 23946333
DOI: 10.1136/annrheumdis-2013-203641
PMCID: PMC4053592

Genes

PTPN22
GCA
CSK

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23946333-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.PMID 23946333Read ↗

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