Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA expression in cytogenetically normal acute myeloid leukemia.

The New England journal of medicine - 1 May 2008

Marcucci Guido, Radmacher Michael D, Maharry Kati, Mrózek Krzysztof, Ruppert Amy S, Paschka Peter, Vukosavljevic Tamara, Whitman Susan P, Baldus Claudia D, Langer Christian, Liu Chang-Gong, Carroll Andrew J, Powell Bayard L, Garzon Ramiro, Croce Carlo M, Kolitz Jonathan E, Caligiuri Michael A, Larson Richard A, Bloomfield Clara D

Abstract excerpt

BACKGROUND: A role of microRNAs in cancer has recently been recognized. However, little is known about the role of microRNAs in acute myeloid leukemia (AML). METHODS: Using microRNA expression profiling, we studied samples of leukemia cells from adults under the age of 60 years who had cytogenetically normal AML and high-risk molecular features--that is, an internal tandem duplication in the fms-related tyrosine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to fms-Like Tyrosine Kinase 3
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Nucleophosmin

Share to Proportional Hazards Models

Share to RNA, Neoplasm

Share to RNA Probes

Share to Transcriptional Regulator ERG

Source

Identifiers

PMID: 18450603
DOI: 10.1056/NEJMoa074256

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA expression in cytogenetically normal acute myeloid leukemia.PMID 18450603Read ↗

MicroRNA expression in acute myeloid leukemia.Semantic proximity Read ↗

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.Semantic proximity Read ↗

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemiaSemantic proximity Read ↗

MicroRNA ‐based therapies: Revolutionizing the treatment of acute myeloid leukemiaSemantic proximity Read ↗

MicroRNAs as New Biomarkers for Diagnosis and Prognosis, and as Potential Therapeutic Targets in Acute Myeloid LeukemiaSemantic proximity Read ↗

Prognostic Significance of Expression of a Single MicroRNA, <i>miR-181a</i>, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B StudySemantic proximity Read ↗

Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia.Semantic proximity Read ↗

MicroRNA-155 expression and function in AML: An evolving paradigm.Semantic proximity Read ↗

Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profilingSemantic proximity Read ↗

Differential expression of specific microRNA and their targets in acute myeloid leukemia.Semantic proximity Read ↗

MicroRNA expression at diagnosis adds relevant prognostic information to molecular categorization in patients with intermediate-risk cytogenetic acute myeloid leukemiaSemantic proximity Read ↗

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.