Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Impacts on hepatitis B virus replication by gene engineering at apical loop region of capsid protein].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Nov 2013

Chen Jiangyan, Huang Rong, Tao Ying, Huang Yuan, Luo Yingying, Huang Ailong, Hu Jieli

Abstract excerpt

Hepatitis B virus (HBV) DNA replication takes place in the viral capsid that consists of 180 or 240 copies of HBV capsid (HBc or core) protein. The monomeric core protein contains an apical loop region that forms the spikes on the surface of viral capsid upon core dimerization and capsid assembly. To investigate the impact on HBV DNA replication through gene engineering at the spike of HBV capsid. plasmids...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Capsid Proteins
Share to Genetic Engineering

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Green Fluorescent Proteins

Share to HEK293 Cells

Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

Share to Recombinant Fusion Proteins

Share to Virus Replication

Source

Identifiers

PMID: 24701831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Impacts on hepatitis B virus replication by gene engineering at apical loop region of capsid protein].PMID 24701831Read ↗

Multiple roles of core protein linker in hepatitis B virus replicationSemantic proximity Read ↗

[The effect of envelope protein mutation on hepatitis B virus assemble].Semantic proximity Read ↗

Inhibition of viral replication by genetically engineered mutants of the duck hepatitis B virus core protein.Semantic proximity Read ↗

Hepatitis B virus core gene mutations which block nucleocapsid envelopment.Semantic proximity Read ↗

Conserved Lysine Residues of Hepatitis B Virus Core Protein Are Not Required for Covalently Closed Circular DNA Formation.Semantic proximity Read ↗

Preparation by alkaline treatment and detailed characterisation of empty hepatitis B virus core particles for vaccine and gene therapy applications.Semantic proximity Read ↗

The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles.Semantic proximity Read ↗

Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations.Semantic proximity Read ↗

Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins.Semantic proximity Read ↗

Synthesis and assembly of Hepatitis B virus envelope protein-derived particles in Escherichia coli.Semantic proximity Read ↗

Extensive mutagenesis of the hepatitis B virus core gene and mapping of mutations that allow capsid formation.Semantic proximity Read ↗

[Construction and expression of plasmids containing different truncated core proteins of hepatitis C virus derived from tumor and non-tumor tissues].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.