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[Construction and expression of plasmids containing different truncated core proteins of hepatitis C virus derived from tumor and non-tumor tissues].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Nov 2004

Yan Xue-bing, Chen Zhi, Delphine Boucreux, Nicole Pavio, Christian Brechot

Abstract excerpt

OBJECTIVE: To study the role of different truncated core proteins (CORE) of hepatitis C virus (HCV) played in the pathogenesis of HCV persistent infection and hepatocellular carcinoma, and to construct seven different truncated prokaryotic expression plasmids of HCV CORE. METHODS: The gene sequences of different truncated HCV genotype 1b CORE were amplified from plasmids containing CORE sequences derived from...

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PMID: 15623368

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