Article
Brain-derived neurotrophic factor gene polymorphism predicts interindividual variation in the sleep electroencephalogram.
Journal of neuroscience research - 1 Aug 2014
Guindalini Camila, Mazzotti Diego R, Castro Laura S, D'Aurea Carolina V R, Andersen Monica L, Poyares Dalva, Bittencourt Lia R A, Tufik Sergio
Abstract excerpt
Previous studies have suggested that brain-derived neurotrophic factor (BDNF) participates in the homeostatic regulation of sleep. The objective of this study was to investigate the influence of the Val66Met functional polymorphism of the BDNF gene on sleep and sleep EEG parameters in a large population-based sample. In total 337 individuals participating in the São Paulo Epidemiologic Sleep Study were selected...
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