Article
Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity.
Biological psychology - 1 Oct 2008
Gatt Justine M, Kuan Stacey A, Dobson-Stone Carol, Paul Robert H, Joffe Russell T, Kemp Andrew H, Gordon Evian, Schofield Peter R, Williams Leanne M
Abstract excerpt
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention. This study aims to identify the mediating neural mechanisms in links between BDNF and depression using highly heritable electroencephalographic (EEG) recordings. In 305 healthy subjects, BDNF Val66Met genotypes were compared in...
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