Article
Serotonergic functioning as measured by the loudness dependence of auditory evoked potentials is related to a haplotype in the brain-derived neurotrophic factor (BDNF) gene.
Journal of psychiatric research - 1 Jun 2010
Juckel Georg, Schumacher Christiane, Giegling Ina, Assion Hans-Jörg, Mavrogiorgou Paraskevi, Pogarell Oliver, Mulert Christoph, Hegerl Ulrich, Norra Christine, Rujescu Dan
Abstract excerpt
OBJECTIVES: The serotonergic system plays an important pathophysiological role in various psychiatric disorders. Brain-derived neurotrophic factor (BDNF) is involved in the differentiation and survival of serotonergic neurons. A previous study showed that low serum BDNF levels were associated with strong loudness dependence of auditory evoked potentials (LDAEP) as a reflection of low central serotonergic...
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