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Article

The association of BDNF gene polymorphism with cognitive impairment in insomnia patients.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2019

Zaki Nevin F W, Saleh Elsayed, Elwasify Mahmoud, Mahmoud Elhasanein, Zaki John, Spence David Warren, BaHammam Ahmed S, Pandi-Perumal Seithikurippu R

Abstract excerpt

BACKGROUND: Reductions in BDNF activity have shown associations with depressed mood. Other evidence has demonstrated that the BDNF Val66Met polymorphism (rs6265) appears to reduce neural plasticity. A limited number of studies have investigated the influence of these genetic polymorphisms in insomnia. The present study sought to confirm the presence of associations between BDNF Val66Met polymorphism (rs6265)...

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Source

Identifiers

PMID: 30076879
DOI: 10.1016/j.pnpbp.2018.07.025

Genes

BDNF
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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