Article
Association of serum BDNF levels and the BDNF Val66Met polymorphism with the sleep pattern in healthy young adults.
PloS one - 1 Jan 2018
Saitoh Kaori, Furihata Ryuji, Kaneko Yoshiyuki, Suzuki Masahiro, Takahashi Sakae, Uchiyama Makoto
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) is widely expressed in the brain and plays an important role in neuronal maintenance, plasticity, and neurogenesis. Prior studies have found that decreased serum BDNF levels are associated with perceived stress, depression, or sleep disturbances in humans. STUDY OBJECTIVES: To elucidate whether the serum BDNF levels and BDNF genotype were associated with the...
Topics
- Adult
- Amino Acid Substitution
- Brain-Derived Neurotrophic Factor
- Female
- Humans
- Male
- Polymorphism, Single Nucleotide
- Sleep
