Article
The Period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegans.
Developmental biology - 15 Jun 2014
Van Wynsberghe Priscilla M, Finnegan Emily F, Stark Thomas, Angelus Evan P, Homan Kathryn E, Yeo Gene W, Pasquinelli Amy E
Abstract excerpt
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate gene expression in many multicellular organisms. They are encoded in the genome and transcribed into primary (pri-) miRNAs before two processing steps that ultimately produce the mature miRNA. In order to generate the appropriate amount of a particular miRNA in the correct location at the correct time, proper regulation of miRNA biogenesis is...
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