Article
Cross-talk between malarial cysteine proteases and falstatin: the BC loop as a hot-spot target.
PloS one - 1 Jan 2014
Sundararaj Srinivasan, Saxena Ajay K, Sharma Ruby, Vashisht Kapil, Sharma Supriya, Anvikar Anup, Dixit Rajnikant, Rosenthal Philip J, Pandey Kailash C
Abstract excerpt
Cysteine proteases play a crucial role in the development of the human malaria parasites Plasmodium falciparum and Plasmodium vivax. Our earlier studies demonstrated that these enzymes are equipped with specific domains for defined functions and further suggested the mechanism of activation of cy...
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