Article

Comprehensive Approach to in silico Identification and in vitro Validation of Anti-Filarial Lead Molecules Targeting the Dimer Interface of Thioredoxin Peroxidase 1 in Wuchereria bancrofti: A Progress in Anti-Filariasis Drug Development

2024-02-28

Abstract excerpt

Lymphatic filariasis (LF) remains a significant health challenge for populations in developing countries, including India. LF is a parasitic disease transmitted by mosquitoes, caused by three types of nematodes: Wuchereria bancrofti, Brugia malayi , and Brugia timori , prevalent in tropical and subtropical regions. Filarial nematodes are transmitted to humans by infected mosquitoes carrying L3 larvae during a bloo...

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Literature Corpus work: 8c5957d3-4ca0-5042-ba99-e48330ab543c
DOI: 10.21203/rs.3.rs-3982867/v1

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Comprehensive Approach to in silico Identification and in vitro Validation of Anti-Filarial Lead Molecules Targeting the Dimer Interface of Thioredoxin Peroxidase 1 in Wuchereria bancrofti: A Progress in Anti-Filariasis Drug DevelopmentDOI 10.21203/rs.3.rs-3982867/v1Read

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