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Multi‐marker analysis of circulating cell‐free DNA toward personalized medicine for colorectal cancer

24 Mar 2014

Abstract excerpt

Development of a Q-PCR-based assay for the high-performance analysis of circulating cell-free DNA (ccfDNA) requires good knowledge of its structure and size. In this work, we present the first visual determination of ccfDNA by Atomic Force Microscopy (AFM) on plasma samples from colorectal cancer (CRC) patients and healthy donors. In addition to the examination of fragment size distribution profile as performed...

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PMID: 24698732
DOI: 10.1016/j.molonc.2014.02.005

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