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Article

Cell‐free DNA copy number variations in plasma from colorectal cancer patients

15 May 2017

Abstract excerpt

To evaluate the clinical utility of cell‐free DNA (cfDNA), we performed whole‐genome sequencing to systematically examine plasma cfDNA copy number variations (CNVs) in a cohort of patients with colorectal cancer (CRC, n = 80), polyps (n = 20), and healthy controls (n = 35). We initially compared cfDNA yield in 20 paired serum–plasma samples and observed significantly higher cfDNA concentration in serum (median =...

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PMID: 28504856
DOI: 10.1002/1878-0261.12077

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