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Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

30 Aug 2018

Abstract excerpt

Improving early detection of colorectal cancer (CRC) is a key public health priority as adenomas and stage I cancer can be treated with minimally invasive procedures. Population screening strategies based on detection of occult blood in the feces have contributed to enhance detection rates of localized disease, but new approaches based on genetic analyses able to increase specificity and sensitivity could provide...

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PMID: 30166531
DOI: 10.1038/s41419-018-0934-x

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