Article
TET2 overexpression in chronic lymphocytic leukemia is unrelated to the presence of TET2 variations.
BioMed research international - 1 Jan 2014
Hernández-Sánchez María, Rodríguez Ana Eugenia, Kohlmann Alexander, Benito Rocío, García Juan Luis, Risueño Alberto, Fermiñán Encarna, De Las Rivas Javier, González Marcos, Hernández-Rivas Jesús-María
Abstract excerpt
TET2 is involved in a variety of hematopoietic malignancies, mainly in myeloid malignancies. Most mutations of TET2 have been identified in myeloid disorders, but some have also recently been described in mature lymphoid neoplasms. In contrast to the large amount of data about mutations of TET2, some data are available for gene expression. Moreover, the role of TET2 in chronic lymphocytic leukemia (CLL) is...
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