Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice.

Scientific reports - 12 Aug 2020

Akkaya Munir, Bansal Abhisheka, Sheehan Patrick W, Pena Mirna, Cimperman Clare K, Qi Chen Feng, Yazew Takele, Otto Thomas D, Billker Oliver, Miller Louis H, Pierce Susan K

Abstract excerpt

Cerebral malaria (CM) is the deadliest form of severe Plasmodium infections. Currently, we have limited understanding of the mechanisms by which Plasmodium parasites induce CM. The mouse model of CM, experimental CM (ECM), induced by infection with the rodent parasite, Plasmodium berghei ANKA (PbANKA) has been extensively used to study the pathophysiology of CM. Recent genomic analyses revealed that the coding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR-Cas Systems
Share to Extracellular Matrix

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Malaria, Cerebral

Share to Mice, Inbred C57BL

Share to Plasmodium berghei

Share to Protozoan Proteins

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 32788672
DOI: 10.1038/s41598-020-70617-7
PMCID: PMC7424516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice.PMID 32788672Read ↗

A single-nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor alters the development of host immunity.Semantic proximity Read ↗

Distinct placental malaria pathology caused by different Plasmodium berghei lines that fail to induce cerebral malaria in the C57BL/6 mouseSemantic proximity Read ↗

Host genetics in malaria: lessons from mouse studies.Semantic proximity Read ↗

Cerebral malaria is regulated by host mediated changes in <i>Plasmodium</i> gene expressionSemantic proximity Read ↗

Characterization of cerebral malaria in the outbred Swiss Webster mouse infected byPlasmodium bergheiANKASemantic proximity Read ↗

Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria.Semantic proximity Read ↗

Association of a determinant on mouse chromosome 18 with experimental severe Plasmodium berghei malaria.Semantic proximity Read ↗

Susceptibility to lethal cerebral malaria is regulated by epistatic interaction between chromosome 4 (Berr6) and chromosome 1 (Berr7) loci in mice.Semantic proximity Read ↗

Detection of a new cerebral malaria susceptibility locus, using CBA mice.Semantic proximity Read ↗

Comparative genomics of Plasmodium yoelii nigeriensis N67 and N67C: genome-wide polymorphisms, differential gene expression, and drug resistance.Semantic proximity Read ↗

Genome Sequence, Transcriptome, and Annotation of Rodent Malaria Parasite Plasmodium Yoelii Nigeriensis N67Semantic proximity Read ↗

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.